Product Information

Product NameFluticasone propionate (IP/BP/EP /USP)
Structure
IUPAC Name6α,9-Difluoro-17-[[fluoromethyl)sulfanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl propanoate

Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,(6 α,11β ,16 α,17 α)-S-(fluoromethyl)ester

S-Fluoromethyl 6α,9α -difluoro-11β -hydroxy-16α -methyl-3-oxo-17α -propionyloxyandrosta-1,4-diene-17β -carbothioate

CAS No.80474-14-2
Molecular formulaC25H31F3O5S
Molecular Weight500.6
AppearanceNature- Solid, Powder
Colour- White or almost white
SolubilityPractically insoluble in water, sparingly soluble in methylene chloride, slightly soluble in ethanol (96 percent)
Melting Range272°C- 275°C
Patent StatusProduct patent – Out of patent
Therap.CatFluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein.
It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn’s disease and ulcerative colitis.
It is also used to treat eosinophilic esophagitis. Treatment of Upper Respiratory Tract Disorders; Corticosteroids