Product Information

Product NameFormoterol Fumarate Dihydrate IP /BP /EP /USP
Structure
IUPAC NameN-[2-Hydroxy-5-[(1RS)-1-hydroxy-2-(4-methoxyphenyl) -1-methylethyl] amino] ethyl] phenyl] formamide (E)-butenedioate dihydrate

(±)-2’-Hydroxy-5’-[(R*)-1-hydroxy-2-[[(R*)-p-methoxy-α -methylphenethyl]amino]ethyl]formanilide fumarate (2:1) (salt), dihydrate

CAS No43229-80-7
AppearanceNature- Solid (powder)
Colour- White or almost white or slightly yellow
Molecular FormulaC42H52N4O12, 2H2O
Molecular Weight841
Melting Point

138°C-140°C
SolubilityFreely soluble in dimethyl sulfoxide and in acetic acid; soluble in methanol; slightly soluble in water and in 2-propanol; practically insoluble in acetonitrile and in diethyl ether
PolymorphismYes
Patent statusProduct patent – Out of patent
Therap.CatFormoterol is a long-acting β2 agonist that has an extended duration of action (up to 12hours) compared to short-acting and agonists such as Salbutamol (Albuterol), which are effective for 4 to 6 hours.