Product Information

Product NameIsoxsuprine Hydrochloride IP/BP/EP/USP
IUPAC Name(1RS, 2SR)-1-(4-Hydroxyphenyl)-2-[[(1SR)-1-methyl-2- phenoxyethy]amino]propan-1-ol hydrochloride

Benzenemethanol, 4-hydroxy- α-[1-[(1-methyl-2-phenoxyethyl) amino] ethyl]-, hydrochloride, stereoisomer

p-Hydroxy-α -[1-[(1-methyl-2-phenoxyethyl) amino]ethyl]benzyl alcohol hydrochloride

(±)-( αR*) -p-Hydroxy-α -[(1S *)-1-[[(1S *)-1-methyl-2-phenoxyethyl]amino]ethyl]benzyl alcohol hydrochloride

CAS No.[579-56-6] and [34331-89-0]
Molecular FormulaC18H23NO3,HCl
Molecular Weight337.8
AppearanceNature-Solid (Crystalline powder)
Colour-White or almost white
Melting RangeAbout 200°C-205°C, with decomposition
SolubilitySlightly soluble in water, (Take 1 g of solute and dissolve in 100 ml to 1000ml of solvent). Sparingly soluble in alcohol, Take 1 g of solute and dissolve in 30 ml to 100ml) of solvent. Practically insoluble in methylene chloride.
Patent StatusOut of patent
Therap.CatIsoxsuprine (used as isoxsuprine hydrochloride) is
a drug used as a vasodilator . Isoxsuprine is a β2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β2receptors.

In humans
Isoxsuprine it is used in humans for treatment of
premature labor, i.e. a tocolytic, and as a vasodilator for the treatment of cerebral vascular insufficiency,
Isoxsuprine may increase the heart rate, cause changes in blood pressure, and irritate the GI tract. It should therefore be used with caution if combined with other drugs that affect blood pressure, such as sedatives and anesthetic drugs.
In horses
Isoxsuprine is most commonly used to treat hoof-related problems in the horse,